Atlas of Pediatric Peripheral Blood Smears

Atlas of Pediatric Peripheral Blood Smears mô tả

Atlas of Pediatric Peripheral Blood Smears là sách atlas về phết máu ngoại biên ở trẻ em. Sách được công Abbott xuất bản dành cho bạn đọc chuyên ngành xét nghiệm. Cuốn sách có nội dung đơn giản như cuốn sổ tay giúp các bạn dễ dàng lại kiến thức.

Atlas of Pediatric Peripheral Blood Smears nội dung

Preface …………………………………………………………………………ii
1. Erythrocyte Morphology: Normal………………………………..1
• Erythrocyte (Red Cell) …………………………………………………………1
• Normal Morphology (Newborn)…………………………………………….1
• Normal Morphology (Infants and Children) ……………………………..2
2. Erythrocyte Morphology: Abnormal…………………………….3
• Acanthocytes (Spur Cells)……………………………………………………3
• Bite Cells………………………………………………………………………….3
• Blister Cells ………………………………………………………………………4
• Echinocytes (Burr Cells, Crenated Cells) ………………………………..4
• Fragmented Red Cells (Schistocytes, Helmet Cells, Keratocytes)…..5
• Macrocytes ………………………………………………………………………5
• Microcytes………………………………………………………………………..6
• Ovalocytes (Elliptocytes) ……………………………………………………..6
• Polychromatophilic Red Cells (Reticulocytes)………………………….7
• Sickle Cells (Drepanocytes)………………………………………………….7
• Spherocytes……………………………………………………………………..8
• Stomatocytes……………………………………………………………………8
• Target Cells (Codocytes)……………………………………………………..9
• Teardrop Cells (Dacrocytes) …………………………………………………9
3. Erythrocyte Inclusions ……………………………………………..10
• Basophilic Stippling ………………………………………………………….10
• Heinz Bodies…………………………………………………………………..10
• Hemoglobin C Crystals……………………………………………………..10
• Hemoglobin H Inclusions…………………………………………………..11
• Howell-Jolly Bodies ………………………………………………………….11
• Pappenheimer Bodies ………………………………………………………11
4. Miscellaneous Abnormalities ……………………………………12
• Agglutination …………………………………………………………………..12
• Rouleaux ……………………………………………………………………….12

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5. Hemolytic Anemias in Pediatrics ………………………………13
• Hereditary Hemolytic Anemias …………………………………………..13
− Membrane Defects ……………………………………………………….13
− Enzyme Defects……………………………………………………………14
– Glucose 6 Phosphate Dehydrogenase Deficiency ……………14
– Pyruvate Kinase Deficiency ………………………………………….14
− Congenital Dyserythropoietic Anemia ……………………………….14
− Hemoglobinapathies ……………………………………………………..15
• Acquired Hemolytic Anemias …………………………………………….16
− Autoimmune Hemolytic Anemia ………………………………………16
− Microangiopathic Hemolytic Anemias……………………………….16
– Hemolytic Uremic Syndrome………………………………………..16
– Thrombotic Thrombocytopenic Purpura…………………………17
– Disseminated Intravascular Coagulopathy………………………17
− Thermal Injury ………………………………………………………………17
• Neonatal Autoimmune Hemolytic Anemias ………………………….17
− ABO Incompatibility ………………………………………………………17
− Rh Incompatibility………………………………………………………….17
6. Non-Hemolytic Anemias in Pediatrics……………………….18
• Pancytopenias…………………………………………………………………18
• Bone Marrow Failure Syndrome………………………………………….18
− Acquired Aplastic Anemia ………………………………………………18
− Fanconi Anemia ……………………………………………………………18
− Diamond Blackfan Anemia ……………………………………………..18
− Dyskeratosis Congenita …………………………………………………18
− Seckel Syndrome………………………………………………………….19
• Autoimmune Pancytopenia………………………………………………..19
• Myelodysplastic Syndrome………………………………………………..19
• Down Syndrome ……………………………………………………………..19
• Microcytic Anemias ………………………………………………………….20
− Iron Deficiency Anemia…………………………………………………..20
− Lead Poisoning ……………………………………………………………20
− Thalassemias ……………………………………………………………….20
• Normocytic Anemias ………………………………………………………..21
• Macrocytic Anemias …………………………………………………………22
• Summary ……………………………………………………………………….22

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7. White Blood Cell Morphology: Normal………………………23
• White Blood Cells (Leukocytes)…………………………………………..23
• Myelopoiesis …………………………………………………………………..23
• Neutrophil, Segmented (segs)…………………………………………….23
• Band Neutrophil ………………………………………………………………23
• Basophil…………………………………………………………………………24
• Eosinophil……………………………………………………………………….24
• Monocytes ……………………………………………………………………..25
• Lymphocytes…………………………………………………………………..25
• Lymphocytes, Large Granular (Atypical Lymphocytes) ……………26
• Reactive Lymphocytes ……………………………………………………..26
• Infectious Mononucleosis ………………………………………………….26
8. White Blood Cell Morphology: Abnormal…………………..27
• Neutrophil Abnormalities: Toxic Changes……………………………..27
− Toxic Granulation ………………………………………………………….27
− Toxic Vacuolization………………………………………………………..27
− Döhle Bodies ……………………………………………………………….27
− Hypersegmented Neutrophils………………………………………….27
− Pelger-Huët Cell Anomaly ………………………………………………28
− Dysplastic Neutrophils……………………………………………………28
− Auer Rods……………………………………………………………………28
9. Platelet Morphology: Normal/Abnormal ……………………29
• Normal Platelets (Thrombocytes) ………………………………………..29
• Large Platelets ………………………………………………………………..29
• Giant Platelets …………………………………………………………………30
• Small Platelets (Microthrombocytes) ……………………………………30
• Hypogranular Platelets (Dysplastic Platelets)…………………………30
• Platelet Satellitism ……………………………………………………………31
• Thrombocytosis……………………………………………………………….31
10. Neoplastic Diseases……………………………………………….32
• Leukemias and Myeloproliferative Diseases ………………………….32
• Lymphoblastic Leukemia …………………………………………………..32
− L1 Lymphoblastic Leukemia……………………………………………32
− L2 Lymphoblastic Leukemia……………………………………………32
− L3 Lymphoblastic Leukemia……………………………………………33

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• Myeloid Leukemia ……………………………………………………………33
− M0 Myeloblastic Leukemia……………………………………………..33
− M1 Myeloblastic Leukemia……………………………………………..33
− M2 Myeloblastic Leukemia……………………………………………..33
− M3 Promyelocytic Leukemia …………………………………………..34
− M4 Myelomonocytic Leukemia………………………………………..34
− M5 Monoblastic Leukemia ……………………………………………..34
− M6 Erythroblastic Leukemia ……………………………………………35
− M7 Megakaryoblastic Leukemia ……………………………………..35
• Myeloproliferative Disorders……………………………………………….36
− Chronic Myelogenous Leukemia ……………………………………..36
− Juvenile Myelomonocytic Leukemia …………………………………36
− Transient Myeloproliferative Disease …………………………………36
11. Miscellaneous………………………………………………………..37
• Infections………………………………………………………………………..37
− Infectious Mononucleosis……………………………………………….37
− Malaria………………………………………………………………………..37
− Borrelia ……………………………………………………………………….37
− Filaria ………………………………………………………………………….37
− Candida Albicans………………………………………………………….37
− Bacteria ………………………………………………………………………38
• Chédiak-Higashi Syndrome ……………………………………………….38
• Storage Diseases …………………………………………………………….39
− Mucopolysaccharidosis………………………………………………….39
− Glycogen Storage Diseases ……………………………………………39
− Lipid Storage Diseases ………………………………………………….39